It is not infrequent that patients come in for cosmetic treatments such as Botox® or a filler like Juvederm® or Restylane® and ask about procedures that are more permanent so that they do not have to come back for more treatments.
For many years, the only filler available was collagen, which lasted only a few months and you had to wait a month after getting a test dose to make sure that you were not allergic to it before your first injection. The hyaluronic acids like Juvederm® and Restylane® can last nine to twelve months and do not require a test dose first. There are risks to filler injections and the result may not always be exactly what you are looking for. If a permanent type of filler was used, that less than perfect result would be permanent. The hyaluronic acid fillers mentioned above also can be dissolved with an injectable enzyme which is not possible with other types of fillers.
The permanent lip enhancers are very unnatural and I have seen many more bad results that good results which is why I have avoided them for many years.